Taurine a potential role in preventing oxidative damage and restoring muscle function in muscular disorders ( Ripps and Shen, 2012 De Luca et al., 2015 Thirupathi et al., 2020). This scenario can demand additional taurine requirements from external sources. For example, high-intensity-induced redox modification of cysteine can undergo several post-translational modifications to produce either muscular adaptation or fatigue, which affects taurine biosynthesis ( Thirupathi et al., 2020). Exercise is a crucial factor that can influence the pattern of biosynthesis of taurine by oxidizing the precursor cysteine. This pattern may be affected by the person's nutritional intake and the availability of its precursor cysteine ( Ripps and Shen, 2012 De Luca et al., 2015). Next, decarboxylation of cysteine sulfinic acid by cysteine sulfinic acid decarboxylase occurs, producing hypotaurine finally, the oxidation of hypotaurine to taurine. The biosynthesis of taurine is as follows: First, cysteine is oxidized by cysteine dioxygenase to form cysteine sulfinic acid. The main sources of dietary taurine are meat, shellfish, sea vegetables, and dairy products. The intracellular concentration ranges of taurine range approximately between 5 and 20 μmol/g in many tissues, particularly in excitable tissues, including skeletal muscle, heart, and brain ( De Luca et al., 2015). However, it has multiple physiological roles, including interacting with ion channels, membrane stabilization, and cellular osmoregulation ( Shihabi et al., 1989 Schaffer and Kim, 2018). Taurine is a prominent free amino acid with little or no role in protein synthesis. Systematic Review Registration:, PROSPERO (CRD42021225243). Finally, we observed that a low dose of taurine (0.05 g) before performing strength enhancing exercises can decrease muscular fatigue and increase enzymatic antioxidants. However, further studies are warranted to establish the role of taurine in fat metabolism during exercise. However, acute administration of taurine (6 g) at a high dose before the start of exercise had no effect on reducing lactate level, but increased glycerol levels, suggesting that taurine could be an effective agent for prolonged activities, particularly at higher intensities. Furthermore, 1 g of acute taurine administration before or after exercise can decrease lactate levels. From the selected literature, we observed that taurine supplementation (2 g three times daily) with exercise can decrease DNA damage. The following parameters were used to assess exercise performance in the selected studies: creatine kinase (CK), lactic acid dehydrogenase, carbohydrate, fat, glycerol, malondialdehyde, enzymatic antioxidants, blood pH, taurine level, and muscular strength. Ten articles were retrieved, reviewed, and subjected to systematic analysis. In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement, relevant articles were sought on PubMed, Medline, Web of Science, and Google Scholar using related terms, including taurine, exercise performance, exercise, muscle, physical training, running, strength, endurance exercise, resistance exercise, aerobic exercise, and swimming. Therefore, this review aimed to systematically review the dose response of taurine on both aerobic and strength exercise performance. However, how this molecule orchestrates such functions is unknown, particularly the dose response in exercised muscles. Taurine is a naturally occurring amino acid involved in various functions, including regulating ion channels, cell volume, and membrane stabilization.
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